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BIS Member Paper Higlight: Epigenomic preconditioning of peripheral monocytes determines their transcriptional response to the tumor microenvironment, Genome Med, 2025.
Abstract. Monocytes are recruited to tumors and undergo transcriptional reprogramming resulting in tumor-promoting functions. It remains unknown whether systemic tumor-derived signals could alter the epigenomic landscape of peripheral monocytes before they reach the tumor, thus shaping their subsequent response to the tumor microenvironment. Here, we performed genome-wide analyses of multiple histone modifications (H3K4me1, H3K4me3, H3K27ac)… Read more
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BIS Member Paper Higlight: Depleting IL1R2+ Tumor-Infiltrating Regulatory T Cells with an ADCC-Prone Nanobody Construct Boosts the Efficacy of Anti-PD1 Immunotherapy, Arnouk et a., Cancer Res 2025
Abstract. Eliminating immunosuppressive cells, such as regulatory T cells (Tregs), is a promising approach to boost immunotherapy success. However, this approach may suffer from systemic auto-immune adverse events, highlighting the need to specifically target tumor-infiltrating (ti)Tregs. We identified IL1R2 as a surface marker that was most highly expressed by activated and strongly T-cell suppressive tiTregs… Read more
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Register now for SenAP Symposium 2025
In 2023, the first edition of the Senescence in Aging and Pathology (SenAP) Symposium took place. After its great success, we are happy to announce a second edition, which will take place on October 7th in Diepenbeek (Embuild building). As you know from the previous edition, our symposium covers the exciting topic of cellular senescence, which has… Read more
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5th European Chemokine and Cell Migration Conference (ECMC 2025)
Date: August 18th-21st, 2025 Venue: Panum Institute, University of Copenhagen, Denmark It is our pleasure to welcome you to Copenhagen for the 5th European Chemokine and Cell Migration Conference (ECMC) to be held at the Panum Institute, University of Copenhagen. The conference will provide a forum for researchers at all career stages to share and… Read more
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Call: Applications for the 2025 EJI Ita Askonas Prize awarded by EFIS
Established in 2009 by EFIS and the European Journal of Immunology (EJI), the prize acknowledges female group leaders with an outstanding track record of achievement in immunology who have run an independent laboratory for a minimum of four and no more than ten years. The prize consists of a €20,000 cash award, plus support for travel, accommodations… Read more
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Deadline Membership Renewal BIS 2025
It’s time to renew your Belgian Immunological Society membership for 2025! 🎉 Membership fees:🔹 PhD student: €20🔹 Postdoc: €30🔹 Academic scientist: €50🔹 Non-academic scientist: €75 📅 Deadline: March 17, 2025 Once your payment is received, you’ll get a proof of membership via email (no invoices issued). 👥 Group payments are possible! Just include all names… Read more
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Belgian Immunological Society 